A quick glance at the NFL's rushing yards leaderboard through five weeks of the 2016 Barry Sanders Jersey season will show a rookie ( of the ) right at the top, but the next few names on the list are a bit more familiar. There's the ' , the NFL's leading rusher in 2014. There's , the second-year back that averaged 131.6 total yards per game over his five starts toward the tail end of last season. And then there's the ' , who has finished in the top-five in rushing yards three out of the last five years. McCoy has run for 447 yards in Buffalo's five games, adding three touchdowns and three runs of 20-plus yards as well. And among the 13 backs with at least 75 Jim Cain Jersey rushes, nobody is averaging more than his 5.3 yards per carry. The Bills are taking on the this Sunday, and Niners coach Chip Kelly knows his defense has a tough task in front of it. Kelly on LeSean McCoy: "He has extreme quickne s and ability to make guys mi s. It's going to take all 11 guys on defense." San Francisco 49ers (@49ers) When Kelly says it's going to take all guys guys T.J. Hockenson Jersey to stop McCoy, he's not lying. And Kelly knows firsthand how good McCoy is because he once coached him during their time in Philadelphia together. Oddly enough, Kelly because, well, it was all about the money.Shady, the master of the jump cut, has forced 20 mi sed tackles on his 103 touches this season, per Pro Football Focus tracking data. Only Murray, Johnson, and have forced Levi Onwuzurike Jersey more mi sed tackles overall, and among the 35 backs with 50-plus touches this season, McCoy ranks 10th in the percentage of touches on which he's forced a mi sed tackle. San Francisco' Detroit Lions Men Jersey s players have combined to mi s 30 tackles so far this season, per the same Pro Football Focus data, an average of about six per game. If McCoy breaks six San Francisco tackles on Sunday, things are probably not going to go well for the 49ers, regardle s of what does in his first start.